#WHAT LOCUS DOES SCID SFFECT SERIES#

tritici ( Pgt) in wheat ( Triticum spp.) started in the early 20 th century 1, 2, 3, 4. International efforts toward genetic resistance breeding for controlling stem rust disease caused by Puccinia graminis f. Together, our results show that functional diversification of allelic variants at the SR9 locus involves single and multiple amino acid changes that recognize isolates of wheat stem rust.

#WHAT LOCUS DOES SCID SFFECT SERIES#

The SR9 allelic series found in the B subgenome are orthologs of wheat stem rust resistance gene Sr21 located in the A subgenome with around 85% identity in protein sequences. SR9B and SR9G resistance proteins are also distinguished by only a single amino acid. The only SR9 protein effective against stem rust pathogen race TTKSK (Ug99), SR9H, differs from SR9B by a single amino acid. Each allele encodes a highly related nucleotide-binding site leucine-rich repeat (NB-LRR) type immune receptor, containing an unusual long LRR domain, that confers resistance to a unique spectrum of isolates of the wheat stem rust pathogen. Loss-of-function mutants and/or transgenic complementation are used to confirm Sr9b, two haplotypes of Sr9e ( Sr9e_h1 and Sr9e_h2), Sr9g, and Sr9h. The seven previously reported resistance alleles ( Sr9a, Sr9b, Sr9d, Sr9e, Sr9f, Sr9g, and Sr9h) are characterised using a synergistic strategy. Here, we report the isolation of most of the alleles at wheat stem rust resistance gene locus SR9. Most rust resistance genes thus far isolated from wheat have a very limited number of functional alleles. Nature Communications volume 14, Article number: 7354 ( 2023) Single amino acid change alters specificity of the multi-allelic wheat stem rust resistance locus SR9

What locus does SCID sffect